We patch more than 400 applications
Yes, you can use the same Assignment Profile on as many applications as you like. But only one Assignment Profile can be assigned to an application at a time.
You can use Deployment Schedules for this purpose, which make use of Assignment Profile to accomplished this goal. Learn more about Deployment Schedules here
You can only assign an Assignment Profile to an application that is already deployed to your Intune.
Clear deployment schedule” from the context menu. Now the Status icon will be marked with yellow “Needs approval or not updated yet” as the newest version of the application now is not deployed. To re-initiate the process assign a schedule.